RELAÇÃO ENTRE BISFOSFONATO E PERIIMPLANTITE: Uma revisão sistemática de literatura

Abstract

Bisphosphonates are bone resorption and potent osteoclast inhibitors medicine, which has been considered the best choice therapy in diseases affecting bone metabolism. The aim of this study is analyze the relationship between bisphosphonate therapy and peri-implantitis in patients who were rehabilitated with implants. The methodology used in this study was a qualitative systematic review of the analytical type. For the bibliographic research, the database (PubMed - National Library of Medicine US) was used between August of 1966 and August of 2016, being selected 28 articles. In the data analysis, eight articles were found that showed a diagnosis of osteonecrosis mandibular associated with bisphosphonates, intraoral necrotic bone exposure, number of implants and follow-up, showing some variables such as absence of evidence of bone loss or peri-implantitis with osteonecrosis around implants dental procedures. The results of the research indicate that not only the surgical intervention of a dental implant, but the implant itself, seems to be a continuous risk factor for the development of osteopathology. With oral administration, after a few weeks of ingestion, adequate levels of inhibition of bone resorption may be observed. According to several studies, dental procedures are one of the risk factors for the development of osteonecrosis of the mandible associated with bisphosphonates. Therefore, careful and frequent follow-up of patients with dental implants receiving bisphosphonate therapy is advised.